This paper is based on the data of Section C of China Undergraduate Mathematical Contest in Modeling（2012） to analyze environmental factors on the incidence of stroke. It is given the basic statistical description of the data for stroke incidence patients as well as the skew –normal distribution fitting for stroke onset age. The statistical model between stroke pathogenesis and environmental factors is established, the incidence of stroke cases for genders, occupations, high risk population (between the ages of 60-80) and the peak period ( incidence number no less than 60 ) are also discussed. At the end, some instructive conclusions from the temperature and pressure factors are obtained. A specific warning intervention programs and further improvement scheme are put forward in this paper.